- What it is: A rare inflammatory demyelinating disease of the central nervous system with concentric, ring-like lesions on MRI, usually regarded as a variant of multiple sclerosis.
- Common symptoms: Limb weakness, numbness or tingling, and other sudden neurological changes that develop over days to weeks.
- Conventional care: Neurologist-led care with high-dose corticosteroids for acute attacks, stronger immune-suppressing treatment in severe cases, and rehabilitation.
- How integrative care fits: Supportive care for symptoms such as pain, fatigue and stress, only with your neurology team aware.
- Evidence at a glance: No trials in Baló's concentric sclerosis itself; the evidence is for multiple sclerosis, and it is low in quality.
What is Baló's Concentric Sclerosis?
Baló's concentric sclerosis is a rare inflammatory demyelinating disease of the central nervous system, most often regarded as a variant of multiple sclerosis.[1, 2] On MRI, it shows lesions made of concentric rings, like an onion, in the white matter of the brain, and these reflect alternating bands of damaged and preserved myelin.[1, 2] It needs specialist neurological care, and for a condition like this, we ask that you are under a physician's care for it and that your treating team knows you are receiving complementary care.
Common symptoms
People usually present with acute or subacute neurological decline.[1] In one case series of 10 people, the most common symptoms were limb weakness and tingling or numbness.[3] The symptoms depend on where the lesion is, as in multiple sclerosis, and can include vision problems, numbness, weakness, and bladder, bowel or thinking difficulties.[4]
Causes and risk factors
The cause is not known. The disease is considered immune-mediated, and researchers have made progress in understanding how the layered lesions form, although important questions remain.[1, 5] Debate continues about whether it is a form of multiple sclerosis or a separate entity.[2] Some people with Baló lesions also meet the criteria for multiple sclerosis, and in the case series above the lesions occurred at the start of multiple sclerosis or within it.[1, 3]
How it is diagnosed and treated conventionally
Diagnosis relies on MRI, supported by spinal fluid tests and by ruling out other conditions, and is made by a neurologist.[5, 6] In the case series, all patients had abnormal spinal fluid with oligoclonal bands.[3]
Corticosteroids are the usual first treatment for an acute attack, and specialists debate what maintenance treatment should follow.[2] If the person also meets criteria for multiple sclerosis, standard multiple sclerosis disease-modifying therapy is considered reasonable, and intense immunosuppression may be used in aggressive cases.[1, 5]
Baló's disease was once thought to be always fatal, but MRI has shown that the course varies. Many people have a more benign, self-limiting course with spontaneous remission, while others progress quickly to severe disability.[1, 5]
Why Baló's Concentric Sclerosis calls for a whole-person approach
Baló's concentric sclerosis is an immune attack on the nervous system, and its treatment belongs with neurologists. Because it overlaps with multiple sclerosis, the everyday problems of that disease are also relevant, such as fatigue, pain, sleep, mood and mobility.
Our role is limited to supporting those everyday problems alongside your treatment. It is not aimed at the lesions themselves.
The immune process
Both Baló's disease and multiple sclerosis involve inflammation and loss of myelin in the central nervous system.[1, 4] This is why immune-suppressing treatment is central, and why any herb or supplement must be checked against it.
Symptoms that affect daily life
Management of multiple sclerosis includes attention to bladder and bowel problems, depression, cognitive impairment, fatigue, sexual dysfunction, sleep disturbances and vertigo, in addition to reducing relapses.[4] These are the areas where supportive care may be considered.
Variability and uncertainty
The course of Baló lesions varies from recovery to severe disability, which makes the condition hard to predict.[5, 7] Living with this uncertainty can be stressful, and having support in place matters, though we are not aware of studies of this in Baló's disease.
Acupuncture as supportive care in Baló's Concentric Sclerosis
What the research shows
No clinical trials of acupuncture for Baló's concentric sclerosis were found in PubMed. The nearest evidence is in multiple sclerosis. A 2025 meta-analysis of 11 randomized trials with 574 people found that acupuncture added to medicine improved disability status and quality of life more than medicine alone. The authors graded the certainty as generally low because the trials differed widely, and reported that side effects were rare and mild.[8]
A review of acupuncture for spasticity found moderate-quality evidence of benefit after stroke but not enough evidence to conclude it reduces spasticity in other central nervous system diseases, including multiple sclerosis.[9] These findings cannot be assumed to apply to Baló's disease.
How acupuncture may work
How acupuncture might help in demyelinating disease is not established. We do not claim that it affects the lesions or the immune attack.
What treatment involves
Treatment, if your neurologist agrees, uses fine, sterile, single-use needles, usually left in place for about 20 to 40 minutes, over several visits with reassessment. We would adjust placement for areas of numbness or weakness.
In prospective studies, about 9 in 100 patients had a minor reaction such as brief bleeding, soreness or redness, and serious events occurred in about 1 in 10,000 patients.[10] Tell the practitioner first if you have a bleeding disorder, take blood thinners or immune-suppressing medicine, are pregnant, or have a pacemaker (relevant to electroacupuncture). Because immune-suppressing treatment can raise infection risk, report any fever or illness before a session.
Ayurvedic medicine as supportive care in Baló's Concentric Sclerosis
The Ayurvedic view
Ayurveda has no classical name for Baló's concentric sclerosis. Neurological weakness and numbness are traditionally described under disorders of Vata, the principle said to govern movement and the nervous system. This is a traditional framework, not a biomedical diagnosis.
Therapies that may be used
Ayurvedic care is individualized and may include gentle warm oil massage, diet and daily routine suggestions, stress-reducing practices and herbs chosen for the person. It would be used only alongside your neurological treatment.
Panchakarma procedures are not appropriate during an acute attack or illness, while weak or frail, during pregnancy, or while taking strong immune-suppressing medicines unless your physician agrees.
What the research shows
No clinical trials of Ayurvedic treatment for Baló's concentric sclerosis were found. Turmeric extract (curcumin) has been studied in several autoimmune diseases. A meta-analysis of 31 randomized trials included two in multiple sclerosis, but the authors said the data were too sparse for a meta-analysis in that disease and called for larger trials.[11] Ayurvedic care therefore remains unproven for this condition. Product quality is also a concern, because about one fifth of Ayurvedic medicines bought online contained detectable lead, mercury or arsenic.[12]
Herbal medicine as supportive care in Baló's Concentric Sclerosis
Herbs and formulas that have been studied
No herbal trials in Baló's concentric sclerosis were found. In multiple sclerosis, trials of Chinese herbal medicine added to conventional care often used Chinese angelica (Angelica sinensis), licorice, red peony, prepared rehmannia and silkworm (Bombyx batryticatus).[13]
What the research shows
The evidence is limited and of low methodological quality. A 2025 meta-analysis of 28 trials with 1,971 people with multiple sclerosis found that adding Chinese herbal medicine to conventional treatment lowered disability scores, relapse rate and fatigue scores, and no serious side effects were reported. The authors rated the methodological quality as suboptimal and called for better trials.[14] An earlier meta-analysis of 20 studies in people having an acute relapse reached similar findings but concluded that poor quality and variability limit any recommendation for routine use.[13] Whether the findings apply to Baló's disease is unknown.
Safety and herb-drug interactions
Herbs can interact with medicines. A review of herb-drug interactions reported that St John's wort lowered blood levels of cyclosporine and tacrolimus, with organ rejection in some cases, and that some herbs added to bleeding risk with warfarin.[15] Anyone taking immune-suppressing or disease-modifying drugs needs their neurologist and pharmacist to review every herb first, and herbs should not be used during an acute attack without medical agreement.
Herbs should come from tested sources, because of the metal contamination noted above, and be prescribed individually. Tell us if you are pregnant or breastfeeding, or have liver or kidney disease.
Translating traditional medicine into modern biological language
This is interpretation, not equivalence. Chinese medicine describes neurological weakness and numbness in terms such as wind, phlegm, blood stasis or deficiency of the liver and kidney, and Ayurveda groups them under Vata. Researchers instead describe immune-mediated loss of myelin and ring-shaped lesions.[1, 2]
The meeting point is the supportive aims, such as easing pain and tension, supporting sleep and reducing stress. No study has shown that a TCM pattern or a dosha corresponds to the immune process in Baló's disease.
How this care fits with your medical care
Our care is supportive and works beside your neurologist and any rehabilitation team. Keep your appointments, scans and prescribed treatment. Do not stop or change any medicine, including steroids and disease-modifying or immune-suppressing drugs, without your prescriber. We do not diagnose Baló's disease or treat the lesions.
Please bring your diagnosis, MRI and spinal fluid reports, a full list of medicines and supplements, and the names of your treating doctors.
When to seek urgent medical care
New or worsening neurological symptoms can mean a relapse or another serious problem, and Baló's concentric sclerosis can progress over days to weeks.[1, 5]
- New or rapidly worsening weakness, numbness or loss of coordination
- Sudden loss or change of vision
- Confusion, a seizure, or trouble speaking or understanding
- Trouble swallowing or breathing
- Loss of bladder or bowel control
- Fever or signs of infection while taking immune-suppressing medicine
If any of these occur, call 911 or go to the nearest emergency department.
Frequently asked questions
What is Baló’s concentric sclerosis?
Baló’s concentric sclerosis is a rare inflammatory disease in which the myelin coating of nerve fibers in the brain is damaged in concentric, ring-like patterns seen on MRI. It is usually considered a variant of multiple sclerosis. The course varies from recovery to severe disability, and it is treated by neurologists.
Can acupuncture help people with Baló’s concentric sclerosis?
No trials have tested acupuncture for this disease, so we cannot say it helps. In multiple sclerosis, a meta-analysis of 11 trials found better disability and quality-of-life scores when acupuncture was added to medicine, but the evidence was low in certainty. Any acupuncture here is supportive only and done with your neurologist’s knowledge.
Do Ayurvedic or herbal medicines help with Baló’s concentric sclerosis?
Neither has been tested in trials for this disease. For multiple sclerosis, meta-analyses of Chinese herbal medicine added to standard care report benefits, but trial quality was low. Herbs can interact with immune-suppressing drugs, so they must be reviewed by your physician and prescribed individually.
Can I stop my steroids or disease-modifying medicine if I have supportive care?
No. Supportive care is complementary. Do not stop or change prescribed medicine without your prescriber, and keep your scans and neurology appointments. New or worsening weakness, vision loss or confusion needs urgent medical care.
What should I bring to my first visit?
Bring your diagnosis, recent MRI and spinal fluid reports, a complete list of medicines and supplements, and the names of your treating doctors. This helps us make sure supportive care fits safely with your medical treatment.
Does insurance cover acupuncture for Baló’s concentric sclerosis?
It may. Netra Integrative Health Clinic accepts most major insurance plans that include out-of-network acupuncture benefits, for example Aetna, Blue Cross Blue Shield, Cigna and UnitedHealthcare, and offers a free benefits check. HSA and FSA cards and CareCredit are also accepted. Call (908) 402-7301 to ask about your plan.
References
- Hardy TA, Miller DH. Baló's concentric sclerosis. Lancet Neurol. 2014;13(7):740-6. PMID 24943346. Lancet Neurology review of Baló's concentric sclerosis describing concentric MRI lesions, its variable course and relationship to multiple sclerosis, and uncertainty about treatment.
- Xie JS, Jeeva-Patel T, Margolin E. Baló's concentric sclerosis - A rare entity within the spectrum of demyelinating diseases. J Neurol Sci. 2021;428:117570. PMID 34261000. Review of Baló's concentric sclerosis covering imaging, the debate over whether it is distinct from multiple sclerosis, corticosteroids as first-line therapy and disease-modifying options.
- Etemadifar M, Aghili A, Shojaei S, et al. Balo concentric sclerosis, an emerging variant of multiple sclerosis: A case-series and literature review. J Neuroimmunol. 2025;400:578527. PMID 39842344. Case series of 10 patients with Baló's concentric sclerosis in the context of multiple sclerosis, with weakness and paresthesia, oligoclonal bands, and treatment mainly with rituximab.
- Tafti D, Ehsan M, Xixis KL. Multiple Sclerosis. StatPearls [Internet]. 2024. PMID 29763024. StatPearls chapter on multiple sclerosis covering demyelination, symptoms, diagnosis, disease-modifying therapy and management of symptoms such as fatigue, depression and sleep problems.
- Amini Harandi A, Esfandani A, Pakdaman H, et al. Balo's concentric sclerosis: an update and comprehensive literature review. Rev Neurosci. 2018;29(8):873-882. PMID 29768251. Literature review describing Baló's concentric sclerosis as a rare variant of multiple sclerosis with either rapid severe courses or benign self-limiting remission, diagnosed by MRI.
- Hardy TA, Reddel SW, Barnett MH, et al. Atypical inflammatory demyelinating syndromes of the CNS. Lancet Neurol. 2016;15(9):967-981. PMID 27478954. Lancet Neurology review of atypical inflammatory demyelinating syndromes, including Baló's concentric sclerosis, and the difficulty of diagnosis and classification.
- Fonseca A, Santos E, Taipa R. Baló concentric sclerosis: Literature review and report of two cases. J Neuroimmunol. 2024;392:578370. PMID 38797061. Review and two case reports showing varied clinical courses and treatment responses in Baló's concentric sclerosis, challenging its image as uniformly severe.
- Chen Y, Cui Y, Zhou X, et al. Clinical evidence on acupuncture for symptom improvement in multiple sclerosis. Complement Ther Med. 2025;95:103276. PMID 41161577. 2025 meta-analysis of 11 trials (574 people) of acupuncture added to medicine in multiple sclerosis, improving disability and quality of life, with low-certainty evidence.
- Zhu Y, Yang Y, Li J. Does acupuncture help patients with spasticity? A narrative review. Ann Phys Rehabil Med. 2019;62(4):297-301. PMID 30408516. Narrative review of acupuncture for spasticity finding moderate evidence after stroke but insufficient evidence in other central nervous system diseases including multiple sclerosis.
- Bäumler P, Zhang W, Stübinger T, et al. Acupuncture-related adverse events: systematic review and meta-analyses of prospective clinical studies. BMJ Open. 2021;11(9):e045961. PMID 34489268. Systematic review of 21 prospective studies finding minor acupuncture reactions in about 9 percent of patients and serious events in about 1 per 10,000.
- Zeng L, Yang T, Yang K, et al. Curcumin and Curcuma longa Extract in the Treatment of 10 Types of Autoimmune Diseases: A Systematic Review and Meta-Analysis of 31 Randomized Controlled Trials. Front Immunol. 2022;13:896476. PMID 35979355. Meta-analysis of 31 randomized trials of curcumin in 10 autoimmune diseases, with only two multiple sclerosis trials and calls for larger studies.
- Saper RB, Phillips RS, Sehgal A, et al. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the Internet. JAMA. 2008;300(8):915-23. PMID 18728265. JAMA study finding detectable lead, mercury or arsenic in about one fifth of Ayurvedic medicines purchased over the Internet.
- Song L, Zhou QH, Wang HL, et al. Chinese herbal medicine adjunct therapy in patients with acute relapse of multiple sclerosis: A systematic review and meta-analysis. Complement Ther Med. 2017;31:71-81. PMID 28434474. 2017 meta-analysis of 20 studies of Chinese herbal medicine in acute multiple sclerosis relapse, listing commonly used herbs and noting poor methodological quality.
- Guan X, Wu Y, Jia Q, et al. Efficacy and safety of Chinese herbal medicine for multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. Front Pharmacol. 2025;16:1635833. PMID 41059199. 2025 meta-analysis of 28 trials (1,971 people) of Chinese herbal medicine added to conventional care in multiple sclerosis, with benefits on disability, relapse and fatigue but suboptimal trial quality.
- Hu Z, Yang X, Ho PC, et al. Herb-drug interactions: a literature review. Drugs. 2005;65(9):1239-82. PMID 15916450. Literature review of herb-drug interactions, including St John's wort lowering cyclosporine and tacrolimus levels and herbs increasing bleeding risk with warfarin.
This page is for general education and is not medical advice. Acupuncture, Ayurvedic medicine and herbal medicine are complementary therapies; they do not replace diagnosis or treatment by your physician. Do not stop or change prescribed treatment without talking to your prescriber. In an emergency call 911.
























